"Bruce Almighty"
http://en.wikipedia.org/wiki/Bruce_Almighty"
Budget $81 million
Gross revenue $484,592,874
In terms of dollar-for-dollar investment-return, making it one of the biggest grossing comedy films of all time. There was a pseudo-'sequel'/spinoff made:
"Evan Almighty"
http://en.wikipedia.org/wiki/Evan_Almighty
Budget $200 million
Gross revenue $173,418,781
It became - dollar-for-dollar return-wise, the biggest comedy flop of all time. One reason why, as critics have said, is that - unlike the first with Jim Carrey - it essentially shovelled the Biblical theme down the throats of it's viewers. Whereas, if anything, the Jim Carrey film was an intriguing & intelligently humourous 'What If...?' scenario: what if you were God? With little to no overtly religious content whatsoever.
The "Harry Potter" films:
http://en.wikipedia.org/wiki/Harry_Potter_%28film_series%29
Budget Total (7 films):
$1,280,000,000
Gross revenue Total (7 films):
$6,343,865,842
Warner Bros, in buying the film rights from JK Rowling, made a wise investment. That studios' shareholders will be very happy. As of course is Ms. Rowling. And the last (half-)film has yet to be released; including potential DVD/Blu-Ray sales.
As opposed to, say, "Left Behind: The Movie":
http://en.wikipedia.org/wiki/Left_Behind:_The_Movie
Budget $4,000,000
Gross revenue $4,224,065
Moral: Sex sells. Fantasy sells. Religion doesn't. You do the maths, Kenny-boy.
But hey, it's your money. If you want to throw it away - a la "Left Behind" - you go right ahead. Only - if you're using mainly funding from other investors - you've got a lot of explaining to do to said others, if this film of yours bombs worse than the Hindenburg. Then I think you'll find that these people worship Mammon more than God. To say nothing of their lawyers, nay, the debt recovery agencies they'll hire.
Hopefully, you'll realise that only one thing matters in film-making: Money. Only the likes of Steven Spielberg, Michael Bay, Guillermo del Toro - and especially James Cameron - can afford to be auteurs these days. So unless "The Life Zone" is bigger than "Avatar", your film will itself become a box-office, nay, a critical abortion.