There is no special risk with GMOs, or even any mechanism by which they could potentially pose a special health risk. GMOs undergo extensive safety tests, while normal crops do not. And no, GMO seeds are actually highly profitable for, and well-received by, those poor Third World small farmers anti-GMO activists like to claim to champion - GMO hysteria is pretty much a pure First World, and in particular European, phenomenon. And there is so much good GMOs can do for us, especially considering just how much crops are lost to disease and spoilage.
GMO hysteria is a manufactruversy born from technophobia, with a good helping of lobbying and FUD from the established agriculture industry and the health woo industry.