There are already seven or more groups fighting and taking each other out in Syria. One more would just complicate matters even more.
I'm a monthly payer to the Red Cross and to Doctors Without Borders, and I'm a taxpaying member of the Swedish Church which does much good among the poor and needy in Sweden and elsewhere. When it's Fathers' or Mothers' Day, I buy rescue packages from UNHCR, the Red Cross or some other relief organization, in mom's and dad's name. Last Christmas, the adults in the family bought different rescue packages to each other. Hubby and me got about 10 gift certificates and the other four families got about as many as well. When you have what you need and what you want (well, some of it) and it becomes more of a chore than a pleasure to write a wish-list, helping people in need with the money is a much saner option.