one of the reasons for which males are the main producers of genetic illnesses into thespecies is for their deficient production of gametes, as only less than the half percent of them are actually viable for reproduction and they tend to produce and accumulate genetic deformities in their gametes as well as in their Y chromosome (for which it's so deteriorated asit cannot recombine). while the female X chromosome has more than 1,000 genes, some as important as for create the human brain, the male Y chromosome is not only so much smaller than its female counterpart, but barely arrives to 45 genes, being most of them useless. in thenature, outside mammals, so many females can reproduce through parthenogenesis or other ways that don't require males, while the opposite doesn't exist. in fact, scientists tried to replicate this methods in female mammals, discovering two male parasitic genes disabling thatcapacity in female mammals. thanks to science, they have already made two female mice to have healthy offspring together, just by substituting the male cell by a female one, something that is not possible the other way around, as two male cells cannot create life, either puttinga fertilized egg inside a male, as males cannot create life and don't have any "seed", as the seed of life is the egg and the female X chromosome, the only chromosome needed for life. you can read biology and genetic studies about this.two of the most famous geneticists as are Bryan Sykes and Steve Jones literally label males as "parasites" to females and a "genetic waste", for what i have said between other reasons. you can read their studies in which they explain it in a so much better and detailed way.