(from a thread about annoying commercials)

The commercial for the new HIV prep drug, Descovy, annoy the hell out of me. Specifically the bit where one of the actors says that it hasn't been tested on people who were assigned "female" at birth. No, you mean people born female. The actual biological sex they were born as. Because all but small percentage of people were born either male or female. It's not like gender, which is cultural and something you can be assigned, it's a biological fact.

So basically this drug hasn't been tested for anyone who was born female, regardless of how they might identify now. Just say that.