They can use this as a way to get the people who don't vaccinate to self identify by luring them into "you don't have to come back to the office, you can work from home".
Once people have been identified they will have the list of people to let go.
Read this and substitute Jew for Antivaxer:
Using the term antivaxer is the first step to dehumanizing people.
Next, comes "the antivaxers have a choice" conversations and some of them do, some have a mental block (could be called mental illness), some may have what they perceive as a healthy fear of the government, which is justified as the government has done some pretty shady things like giving people Syphilis under the guise of medical care.